2 - Pressure on nerves
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Central effect of intravenous phenylephrine on baroreflex control of renal nerves.
Responses of renal sympathetic nerve activity were determined in eight chloralose-anesthetized rabbits during sustained (1-3 minutes) increases in arterial pressure induced by phenylephrine infusion, and as arterial pressure returned to control. In four of the eight experiments, aortic baroreceptor traffic was also recorded. When arterial pressure was raised from 81 +/- 5 to 110 +/- 7 mm Hg, re...
متن کاملImpaired responsiveness of renal mechanosensory nerves in heart failure: role of endogenous angiotensin.
Increasing renal pelvic pressure results in PGE(2)-mediated release of substance P. Substance P increases afferent renal nerve activity (ARNA), which leads to a reflex increase in urinary sodium excretion (U(Na)V). Endogenous ANG II modulates the responsiveness of renal mechanosensory nerves. The ARNA and U(Na)V responses are suppressed by low- and enhanced by high-sodium diet. We examined whet...
متن کاملEffects of sympathetic nerves on cerebral vessels during acute, moderate increases in arterial pressure in dogs and cats.
We studied: (1) the effects of an abrupt, moderate increase in arterial pressure on total and regional cerebral blood flow (CBF) and (2) whether sympathetic stimulation attenuates the transient hyperemia that occurs during a sudden increase in pressure within the physiological range of pressure. Abrupt increases in arterial pressure were produced by occlusion of the descending aorta. Cerebral b...
متن کاملDietary sodium loading increases arterial pressure in afferent renal-denervated rats.
In rats fed high sodium diet, increasing renal pelvic pressure > or =3 mm Hg activates renal mechanosensory nerves, resulting in a renorenal reflex-induced increase in urinary sodium excretion. The low activation threshold of the renal mechanosensory nerves suggests a role for natriuretic renorenal reflexes in the regulation of arterial pressure and sodium balance. If so, interruption of the af...
متن کاملEffects of sympathetic nerves on cerebral blood flow in awake dogs.
Although cerebral blood vessels are densely innervated by sympathetic nerve fibers, the functional significance of the nerves is controversial. Because previous studies have been primarily performed in anesthetized animals, it is possible that failure to observe prominent neural control of the cerebral circulation was secondary to anesthetic-induced depression of the sympathetic nervous system....
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تاریخ انتشار 2013